About Acthar

Learn about Acthar for psoriatic
arthritis flares

Acthar is an FDA-approved short term prescription medicine for treating psoriatic arthritis flares.

Acthar is used to treat flares. It is given in combination with other medicines to help manage flares in psoriatic arthritis symptoms. Acthar contains a highly purified, naturally occurring hormone called ACTH (adrenocorticotropic hormone), which is thought to play a role in the body’s immune system and its response to inflammation.

Acthar is not a steroid.

Why consider Acthar for my psoriatic arthritis?

You may want to consider Acthar because it is:

  • An FDA-approved prescription medicine used as a short-term add-on therapy in the event of symptoms of psoriatic arthritis suddenly worsening (flare)
  • A treatment that has been used in a variety of inflammatory and autoimmune diseases including psoriatic arthritis, rheumatoid and juvenile rheumatoid arthritis, and ankylosing spondylitis
  • May be helpful if you need additional treatment when you experience a flare

What do I need to know about Acthar?

Acthar may not be suitable for all patients with psoriatic arthritis

While taking Acthar, tell your doctor if you have any of these symptoms:
Infections; adrenal gland changes; increased blood pressure, body salt and fluid levels; unpredictable response to vaccines; stomach or intestinal problems; changes in mood or behavior; worsening of other medical conditions; eye problems; or allergic reactions. Tell your doctor about any health problems or any other medicines you are taking.

How Acthar is thought to work

Acthar is believed to work differently than other medicines.

One way it is thought to work is by helping your body produce its own natural steroid hormones such as cortisol. These hormones may assist your immune system by helping your body defend itself against inflammation.

Although the exact way Acthar works in the body is not completely understood, more research is being conducted. This information is based on laboratory data, and how it relates to patient benefit is unknown.


Psoriatic arthritis flares can vary in intensity from person to person, and may even change locations in the same person over time

Important Safety Information

Who should  NOT take Acthar?

You should not take Acthar if you have:

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